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What are the disorders included in the Newborn Screening (Ao 121 s. 2003)

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What are the disorders included in the Newborn Screening (Ao 121 s. 2003)

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The Administrative Order No. 121 s. 2003 by the Department of Health in the Philippines mandates the inclusion of six disorders in the Newborn Screening. These disorders are:

  1. Congenital Hypothyroidism (CH): This is a condition that affects the thyroid gland, which is responsible for producing hormones that are essential for growth and brain development.

  2. Congenital Adrenal Hyperplasia (CAH): This is a group of inherited conditions that affect the adrenal glands. These glands produce hormones that regulate the body's metabolism, immune system, blood pressure, and other essential functions.

  3. Phenylketonuria (PKU): This is a rare genetic disorder that affects a person's ability to metabolize the amino acid phenylalanine. Untreated PKU can lead to intellectual disability, seizures, and other serious health problems.

  4. Galactosemia: This is a condition that affects the body's ability to process the simple sugar galactose, which is found in all foods that contain lactose. If untreated, galactosemia can lead to liver damage, intellectual disability, and other complications.

  5. Glucose-6-Phosphate Dehydrogenase Deficiency (G6PD): This is a condition that affects red blood cells, which carry oxygen from the lungs to the rest of the body. People with G6PD deficiency have red blood cells that break down prematurely.

  6. Maple Syrup Urine Disease (MSUD): This is a rare genetic disorder that prevents the body from breaking down certain amino acids. If untreated, MSUD can lead to seizures, coma, and death.

These disorders are included in the Newborn Screening because early detection and treatment can prevent serious health problems and improve the quality of life for affected individuals.

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