Nucleophilic attack by the carbonyl on the peroxyacid. The carbonyl group is reformed with simultaneous migration of an alkyl group. The nucelophilic attack on the carbonyl group by the peroxyacid. A proton transfer. Save for LaterSubmit Answer
Question
Nucleophilic attack by the carbonyl on the peroxyacid. The carbonyl group is reformed with simultaneous migration of an alkyl group. The nucelophilic attack on the carbonyl group by the peroxyacid. A proton transfer. Save for LaterSubmit Answer
Solution
It seems like you're describing the steps of a Baeyer-Villiger Oxidation, but your question is not clear. Here's a general step-by-step process for a Baeyer-Villiger Oxidation:
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Nucleophilic attack by the carbonyl oxygen on the peroxyacid: The carbonyl oxygen of the ketone or aldehyde attacks the electrophilic peracid (usually MCPBA or m-CPBA), forming a tetrahedral intermediate.
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Proton transfer: A proton is transferred from the oxygen of the peracid to the oxygen of the carbonyl, stabilizing the negative charge.
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Migration of an alkyl group: The alkyl group adjacent to the carbonyl carbon migrates to the oxygen carrying the extra proton. This migration can be either of the alkyl or aryl group attached to the carbonyl carbon. The migrating group is usually the one that can best stabilize a positive charge.
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The carbonyl group is reformed: The carbonyl group is reformed, and a carboxylic acid is released.
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The final product is an ester (from a ketone) or a carboxylic acid (from an aldehyde).
Please provide more specific details if you need a more detailed answer.
Similar Questions
The first step in the Baeyer-Villiger oxidation mechanism is which of the following?Select answer from the options belowNucleophilic attack by the carbonyl on the peroxyacid. A proton transfer. The nucelophilic attack on the carbonyl group by the peroxyacid. The carbonyl group is reformed with simultaneous migration of an alkyl group.
Select the step that comes first in nucleophilic addition that is performed under acidic conditions.Select answer from the options belowThe carbonyl group is protonated by the acid.The anionic intermediate is protonated upon treatment with a mild proton source.The nucleophile attacks the protonated carbonyl group.
Which of the following reactions is an example of nucleophilic substitution reaction ?
The mechanism for the alkylation of terminal alkynes involves which step?Select answer from the options belowNucleophilic AttackLoss of a Leaving GroupCarbocation rearrangementSave for LaterSubmit Answer
During a Baeyer-Villiger oxidation reaction, the peroxyacid (RCO3H) is converted into ________________.Select answer from the options belowcarbon dioxide (CO2)an alcohol (ROH)a carboxylic acid (RCO2H)an ester (RCO2R)
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