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Which of the following is an antidepressant agent that selectively inhibits serotonin uptake with minimal effect on norepinephrine uptake?A.MaprotilineB.DespiramineC.FluoxetineD.Protriptyline

Question

Which of the following is an antidepressant agent that selectively inhibits serotonin uptake with minimal effect on norepinephrine uptake?A.MaprotilineB.DespiramineC.FluoxetineD.Protriptyline

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Solution

The answer is C. Fluoxetine. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that primarily affects the reuptake of serotonin with minimal effect on the reuptake of norepinephrine. This makes it an effective antidepressant. The other options listed, Maprotiline, Desipramine, and Protriptyline, are not SSRIs and have different mechanisms of action.

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