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Which of the following molecules does NOT have all the required components of a nucleotide?NADHFADH2Coenzyme AadenosineAMP

Question

Which of the following molecules does NOT have all the required components of a nucleotide?NADHFADH2Coenzyme AadenosineAMP

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Solution

A nucleotide is composed of three components: a nitrogenous base, a five-carbon sugar (pentose), and at least one phosphate group.

  1. NADH: Nicotinamide adenine dinucleotide (NADH) is a coenzyme found in all living cells. It is a dinucleotide, because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine base and the other nicotinamide.

  2. FADH2: Flavin adenine dinucleotide (FADH2) is a redox cofactor involved in several important reactions in metabolism. FADH2 is a dinucleotide consisting of adenine and flavin mononucleotide.

  3. Coenzyme A: Coenzyme A is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. It does not have a nitrogenous base, which is a required component of a nucleotide.

  4. Adenosine: Adenosine is a nucleoside consisting of a molecule of adenine attached to a ribose sugar molecule. It lacks the phosphate group required for a nucleotide.

  5. AMP: Adenosine monophosphate (AMP) is a nucleotide, composed of a phosphate group, the sugar ribose, and the nucleobase adenine.

So, the molecule that does not have all the required components of a nucleotide is Coenzyme A.

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