Normal cells and cancer cells act very differently. Normal cells respond to certain regulatory factors that cancer cells ignore. Which of these factors are ignored by cancer cells?Select THREE correct answers.Select one or more:a.DNA repairb.Induced cell deathc.Transcription factorsd.Translation factorse.Contact with neighboring cellsf.Temperature
Question
Normal cells and cancer cells act very differently. Normal cells respond to certain regulatory factors that cancer cells ignore. Which of these factors are ignored by cancer cells?Select THREE correct answers.Select one or more:a.DNA repairb.Induced cell deathc.Transcription factorsd.Translation factorse.Contact with neighboring cellsf.Temperature
Solution
The three correct answers are:
a. DNA repair b. Induced cell death e. Contact with neighboring cells
Cancer cells often ignore these regulatory factors. They can bypass the DNA repair process, which allows them to accumulate mutations and evolve rapidly. They can also ignore signals for induced cell death, or apoptosis, which is a mechanism that normal cells use to prevent the proliferation of damaged cells. Lastly, cancer cells can ignore contact inhibition, a process where normal cells stop dividing when they come into contact with other cells. This allows cancer cells to grow and divide uncontrollably, forming tumors.
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