B cells, but not T cells, undergo affinity maturation. This may explain why only _______.1 pointT cells require co-receptors for stable bindingB cells produce a variety of classes of receptorT cells do not produce soluble versions of their receptorsB cells can present antigen on class I MHC
Question
B cells, but not T cells, undergo affinity maturation. This may explain why only _______.1 pointT cells require co-receptors for stable bindingB cells produce a variety of classes of receptorT cells do not produce soluble versions of their receptorsB cells can present antigen on class I MHC
Solution
To answer the question, we need to understand the concepts involved:
- Affinity Maturation: This is a process that occurs in B cells where their receptors (antibodies) undergo mutations to increase their binding affinity to an antigen.
- T Cells: These cells do not undergo affinity maturation and their receptors (TCRs) do not change after they are produced.
- Co-receptors: T cells require co-receptors (like CD4 or CD8) to stabilize their interaction with antigens presented by MHC molecules.
- Soluble Receptors: B cells can produce antibodies, which are soluble versions of their receptors, while T cells do not produce soluble TCRs.
- MHC Class I Presentation: Both B cells and T cells can present antigens on MHC class I molecules, but this is not directly related to affinity maturation.
Given these points, the correct answer is:
T cells do not produce soluble versions of their receptors
This is because affinity maturation in B cells leads to the production of high-affinity antibodies, which are soluble versions of their receptors. T cells, on the other hand, do not produce soluble versions of their receptors, and this is not influenced by affinity maturation.
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