Effector: Synergistically, PTH and calcitriol (vitamin D) increase low blood calcium levels. Osteoclast activity is stimulated by PTH, which promotes bone release and resorption of calcium into the blood (Khan et al., 2022). Furthermore, PTH stimulates the kidneys to convert vitamin D from inactive to active form, calcitriol. This will encourage calcium absorption in the small intestine, increasing blood calcium levels. Together, these mechanisms elevate calcium levels in the blood and restore calcium homeostasis. Increased calcium levels in the serum act as a negative feedback loop, signalling the parathyroid glands to stop the release of PTH is this statement correct?
Question
Effector: Synergistically, PTH and calcitriol (vitamin D) increase low blood calcium levels. Osteoclast activity is stimulated by PTH, which promotes bone release and resorption of calcium into the blood (Khan et al., 2022). Furthermore, PTH stimulates the kidneys to convert vitamin D from inactive to active form, calcitriol. This will encourage calcium absorption in the small intestine, increasing blood calcium levels. Together, these mechanisms elevate calcium levels in the blood and restore calcium homeostasis. Increased calcium levels in the serum act as a negative feedback loop, signalling the parathyroid glands to stop the release of PTH is this statement correct?
Solution
Yes, the statement is correct. The parathyroid hormone (PTH) and calcitriol (active form of vitamin D) do work synergistically to increase low blood calcium levels. PTH stimulates osteoclast activity, leading to bone resorption and release of calcium into the blood. PTH also stimulates the kidneys to convert inactive vitamin D into its active form, calcitriol, which promotes calcium absorption in the small intestine. This process increases blood calcium levels. When calcium levels in the blood increase, it acts as a negative feedback mechanism, signaling the parathyroid glands to stop releasing PTH. This helps to maintain calcium homeostasis in the body.
Similar Questions
Select all direct effects of parathyroid hormone in the body.Multiple select question.Promotes calcium reabsorption by the kidneysPromotes activity of osteoclastsEnhances general cellular metabolic ratesActivates vitamin D in the kidneysDecreases blood calcium levels
A sedentary patient is low in vitamin D, and her calcium levels begin to drop. How will the body respond to bring calcium levels back to normal?Multiple ChoiceIncrease parathyroid hormone secretionIncrease urinary excretion of calciumIncrease calcitonin secretionActivation of osteoblasts
An increased blood calcium level stimulates the release of:Multiple choice question.calcitriolcalcitoninparathyroid hormone (PTH)
What is the role of vitamin D in bone development?Multiple choice question.Vitamin D increases osteoclastic activity and thus helps to break down the bone matrix.Vitamin D decreases calcium absorption through the small intestine and thus prevents excess calcium in the blood which could result in deformed bones.Vitamin D increases calcium absorption in the small intestine and thus helps maintain the calcium concentrations necessary to build the bone matrix.
does this statement make sense Synergistically, PTH and calcitriol increase low blood calcium levels by increasing calcium levels in the serum, which act as a negative feedback loop, signalling the parathyroid glands to stop the release of PTH
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