A sex-linked recessive disorder is inherited on the X chromosome. Which individuals most likely have this disorder?Group of answer choicesmales or females with two copies of the disorder allelemales or females with one copy of the disorder allelemales with one copy of the disorder allele and females with two copies of the disorder allelemales with two copies of the disorder allele and females with one copy of the disorder allele
Question
A sex-linked recessive disorder is inherited on the X chromosome. Which individuals most likely have this disorder?Group of answer choicesmales or females with two copies of the disorder allelemales or females with one copy of the disorder allelemales with one copy of the disorder allele and females with two copies of the disorder allelemales with two copies of the disorder allele and females with one copy of the disorder allele
Solution
The individuals most likely to have a sex-linked recessive disorder are males with one copy of the disorder allele and females with two copies of the disorder allele.
Here's why:
Males have one X and one Y chromosome (XY), while females have two X chromosomes (XX). A sex-linked recessive disorder is one that is carried on the X chromosome.
For males, because they only have one X chromosome, if they inherit the X chromosome with the disorder allele, they will have the disorder because they don't have a second X chromosome that could potentially carry a normal allele to mask the effect of the recessive disorder allele.
For females, because they have two X chromosomes, they would need to inherit the disorder allele on both of their X chromosomes to have the disorder. If they only inherit one disorder allele, they would be carriers of the disorder but would not typically show symptoms because the normal allele on their other X chromosome would mask the effect of the recessive disorder allele.
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