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The proofreading activity, to maintain the fidelity of DNA synthesis,Group of answer choicesis a function of the 3'→5' exonuclease activity of DNA polymerasesis a function of the 5'→3' exonuclease activity of DNA polymerase IIIoccurs only when the DNA polymerase on the lagging strand encounters the previously synthesised fragmentoccurs after the DNA replication process has been completed

Question

The proofreading activity, to maintain the fidelity of DNA synthesis,Group of answer choicesis a function of the 3'→5' exonuclease activity of DNA polymerasesis a function of the 5'→3' exonuclease activity of DNA polymerase IIIoccurs only when the DNA polymerase on the lagging strand encounters the previously synthesised fragmentoccurs after the DNA replication process has been completed

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Solution

The proofreading activity, to maintain the fidelity of DNA synthesis, is a function of the 3'→5' exonuclease activity of DNA polymerases. This activity allows the DNA polymerase to remove incorrectly paired nucleotides, ensuring that the DNA sequence is accurately replicated. This process occurs during DNA replication, not after it has been completed. It is not specific to the lagging strand or to DNA polymerase III, but is a general feature of most DNA polymerases.

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Similar Questions

Which is true of the 5' - 3' exonuclease activity of DNA polymerase I?Group of answer choicesIt proofreads the DNA replication process of polymerase IIt can remove RNA primers via hydrolysis of their phosphodiester backbone linkages.It proofreads the DNA replication process of polymerase IIIIt is involved in synthesis of Okazaki fragments on the lagging strand.

Which of the following reactions is required for proofreading during DNA replication by DNA polymerase III?Group of answer choices5'→3' exonuclease activity3'→5' endonuclease activity5'→3' endonuclease activity3'→5' exonuclease activity

Which is true of the exonuclease activity of DNA polymerase III?Group of answer choicesIt is used to replace an RNA nucleotide from the primer sequence with a DNA nucleotide.It is involved in phosphodiester bond hydrolysis at the 5’ end of a DNA strand.It moves in the 5’ to 3’ direction on the replicated strandThe product of its enzymatic activity is dAMP, dCMP, dGMP or dTMP.

Proofreading activity to maintain the fidelity of DNA synthesis:Select one:a. Requires the presence of an enzyme separate from the DNA polymeraseb. Occurs in prokaryotes but not in eukaryotesc. Occurs after the synthesis has been completed

Which activity of DNA polymerase I is its 'proofreading' activityGroup of answer choices5' to 3' exonuclease activityDNA polymerase I doesn't have this activityBoth 5' to 3' and 3' to 5' exonuclease activities3' to 5' exonuclease activity

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