If a pedigree diagram shows that all of the offspring of an affected female are affected, then the disorder is likely _____.Group of answer choicesX-linked recessivemitochondrial DNA mutationautosomal dominantautosomal recessive
Question
If a pedigree diagram shows that all of the offspring of an affected female are affected, then the disorder is likely _____.Group of answer choicesX-linked recessivemitochondrial DNA mutationautosomal dominantautosomal recessive
Solution
The disorder is likely a mitochondrial DNA mutation.
Here's why:
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Mitochondrial DNA is inherited solely from the mother. This means that if a mother has a disorder caused by a mutation in her mitochondrial DNA, all of her offspring will inherit that mutation, regardless of their gender.
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In contrast, X-linked recessive disorders are not always passed from an affected mother to all of her offspring. Sons have a 50% chance of being affected, while daughters have a 50% chance of being carriers.
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Autosomal dominant disorders are also not always passed from an affected parent to all of their offspring.
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