Which of the following statements is/are correct in enzyme kinetics, if S represents the substrate?Group of answer choicesAt very low substrate concentration, the rate of enzyme reaction is zero order with respect to [S].At all substrate concentrations, the rate of enzyme reaction is first order with respect to [S].At very high substrate concentration, the rate of enzyme reaction is first order with respect to [S].At very high substrate concentration, the rate of enzyme reaction is zero order with respect to [S].At all substrate concentrations, the rate of enzyme reaction is zero order with respect to [S].
Question
Which of the following statements is/are correct in enzyme kinetics, if S represents the substrate?Group of answer choicesAt very low substrate concentration, the rate of enzyme reaction is zero order with respect to [S].At all substrate concentrations, the rate of enzyme reaction is first order with respect to [S].At very high substrate concentration, the rate of enzyme reaction is first order with respect to [S].At very high substrate concentration, the rate of enzyme reaction is zero order with respect to [S].At all substrate concentrations, the rate of enzyme reaction is zero order with respect to [S].
Solution
The correct statement is: "At very high substrate concentration, the rate of enzyme reaction is zero order with respect to [S]."
Here's why:
-
"At very low substrate concentration, the rate of enzyme reaction is zero order with respect to [S]." - This statement is incorrect. At low substrate concentrations, the rate of the enzyme reaction is typically first order with respect to [S], meaning the rate is directly proportional to the substrate concentration.
-
"At all substrate concentrations, the rate of enzyme reaction is first order with respect to [S]." - This statement is also incorrect. While the reaction is first order at low substrate concentrations, it becomes zero order as the substrate concentration increases and the enzyme becomes saturated.
-
"At very high substrate concentration, the rate of enzyme reaction is first order with respect to [S]." - This statement is incorrect for the same reason as the previous one. At high substrate concentrations, the enzyme is saturated and the reaction rate becomes independent of the substrate concentration, making it zero order.
-
"At very high substrate concentration, the rate of enzyme reaction is zero order with respect to [S]." - This statement is correct. When the substrate concentration is high and the enzyme is saturated, the reaction rate becomes independent of the substrate concentration, making it zero order.
-
"At all substrate concentrations, the rate of enzyme reaction is zero order with respect to [S]." - This statement is incorrect. The reaction is only zero order at high substrate concentrations when the enzyme is saturated. At lower concentrations, it is first order.
Similar Questions
According to the Michaelis-Menton kinetics theory, when a reaction is performed in zero-order kinetics:Please select the single best answer The substrate concentration is very low and the reaction rate is dependent on the substrate concentration The substrate concentration is in excess and the reaction rate is dependent on the enzyme concentration The enzyme concentration is in excess and the reaction rate is dependent on the substrate concentration The substrate concentration is equal to Km and the reaction rate is dependent on the enzyme concentration
Which statement is correct about the enzyme kinetics shown below?Group of answer choicesalpha = 4; alpha' = 3alpha = 2.5; alpha' = 5alpha = 1.5; alpha' = 3alpha = 3; alpha' = 4alpha = 5; alpha' = 2.5alpha = 3; alpha' = 1.5
Which of the following best describes the assumption made in steady state kinetic analysis?Group of answer choicesThe concentration of the substrate is decreasing.The concentration of the substrate is constant.The formation of the enzyme-substrate complex is the rate-limiting step.The concentration of enzyme-substrate complex is constant.The enzyme-substrate complex is quickly transformed into the product and free enzyme.
Which of the following statements is/are true of enzyme catalysts?Group of answer choicesThey bind to substrates but are never covalently attached to substrate or product.They increase the equilibrium constant for a reaction, thus favoring product formation.They increase the rate at which substrate is converted into product.They lower the activation energy for the conversion of substrate to product.To be effective, they must be present at the same concentration as their substrates.
Which of the following plot(s) is(are) CORRECT for an enzyme that obeysMichaelis-Menten kinetics, assuming [𝑆] ≪ 𝐾?[𝑆] is the concentration of the substrate, 𝐾 is the Michaelis constant, and v0 isthe initial reaction velocity.
Upgrade your grade with Knowee
Get personalized homework help. Review tough concepts in more detail, or go deeper into your topic by exploring other relevant questions.