Familial hypercholesterolemia results in extremely high levels of cholesterol in the blood. The underlying cause of this disease isGroup of answer choicesinhibition of the cholesterol active transport system in red blood cells.poor attachment of cholesterol to the extracellular matrix of cells.a defect in the receptor-mediated endocytosis of cholesterol.defective cell membranes that cannot incorporate cholesterol.
Question
Familial hypercholesterolemia results in extremely high levels of cholesterol in the blood. The underlying cause of this disease isGroup of answer choicesinhibition of the cholesterol active transport system in red blood cells.poor attachment of cholesterol to the extracellular matrix of cells.a defect in the receptor-mediated endocytosis of cholesterol.defective cell membranes that cannot incorporate cholesterol.
Solution
The underlying cause of familial hypercholesterolemia is a defect in the receptor-mediated endocytosis of cholesterol. This means that the cells' receptors that are supposed to take in cholesterol from the bloodstream are not functioning properly, leading to high levels of cholesterol in the blood.
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Familial Hyperlipoproteinemia is cause by a mutation in which of the following.A) ApoAB) ApoBC) VLDLD) LDL receptor
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