Which of the given chemicals is used as ‘clot buster’ in patients who have undergone myocardial infarction leading to heart attack?
Question
Which of the given chemicals is used as ‘clot buster’ in patients who have undergone myocardial infarction leading to heart attack?
Solution
The chemical used as a 'clot buster' in patients who have undergone myocardial infarction leading to a heart attack is Tissue Plasminogen Activator (tPA). This is a serine protease found on endothelial cells (the cells that line the blood vessels) involved in the breakdown of blood clots. It works by converting plasminogen to plasmin, which is the major enzyme responsible for clot breakdown.
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