Which one of the following statements is INCORRECT? Question 8Select one:a.CRH and ACTH are peptide hormones that result in the release of another set of peptide hormones from the adrenal cortex.b.Growth hormone directly causes metabolic effects but no direct growth effects, whereas insulin-like growth factor-1 (IGF-1) directly stimulates bone and soft tissue growth.c.Corticotropin-releasing hormone (CRH) from the hypothalamus stimulates adrenocorticotropic hormone (ACTH) from the anterior pituitary gland. d.Thyrotropin-releasing hormone (TRH) travels to anterior pituitary cells to trigger thyroid-stimulating hormone (TSH) exocytosis.e.Prolactin differs to other anterior pituitary hormones because it is non-tropic and it does not have a dedicated hypothalamic ‘stimulating’ or ‘inhibiting’ hormone.
Question
Which one of the following statements is INCORRECT? Question 8Select one:a.CRH and ACTH are peptide hormones that result in the release of another set of peptide hormones from the adrenal cortex.b.Growth hormone directly causes metabolic effects but no direct growth effects, whereas insulin-like growth factor-1 (IGF-1) directly stimulates bone and soft tissue growth.c.Corticotropin-releasing hormone (CRH) from the hypothalamus stimulates adrenocorticotropic hormone (ACTH) from the anterior pituitary gland. d.Thyrotropin-releasing hormone (TRH) travels to anterior pituitary cells to trigger thyroid-stimulating hormone (TSH) exocytosis.e.Prolactin differs to other anterior pituitary hormones because it is non-tropic and it does not have a dedicated hypothalamic ‘stimulating’ or ‘inhibiting’ hormone.
Solution
The incorrect statement is b. Growth hormone directly causes metabolic effects but no direct growth effects, whereas insulin-like growth factor-1 (IGF-1) directly stimulates bone and soft tissue growth.
This is incorrect because Growth hormone (GH) does have direct growth effects. It stimulates the liver, muscle, cartilage, bone, and other tissues to synthesize and secrete insulin-like growth factor-I (IGF-I), which is responsible for the growth-promoting effects of GH and is required for GH to generate an optimal growth response in the body.
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