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Which of the following enzymes catalyzes the transpeptidation reaction linking amino acids in the growing polypeptide chain? A. Transpeptidase B. Peptidyl transferase C. Aminoacyl-tRNA synthetase D. Translocase

Question

Which of the following enzymes catalyzes the transpeptidation reaction linking amino acids in the growing polypeptide chain? A. Transpeptidase B. Peptidyl transferase C. Aminoacyl-tRNA synthetase D. Translocase

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Solution

The enzyme that catalyzes the transpeptidation reaction linking amino acids in the growing polypeptide chain is Peptidyl transferase (Option B).

Here's a step-by-step explanation:

  1. The process of protein synthesis involves the translation of genetic information encoded in mRNA into a sequence of amino acids to form a polypeptide chain.

  2. This process occurs in the ribosome and involves several enzymes.

  3. Aminoacyl-tRNA synthetase (Option C) is responsible for attaching the correct amino acid to its corresponding tRNA molecule, a process known as "charging" the tRNA.

  4. Translocase (Option D) is involved in the process of moving the tRNA and mRNA down the ribosome during translation.

  5. Transpeptidase (Option A) is an enzyme involved in bacterial cell

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