Encephalitis caused by HSV1 (cold sore virus) commonly involves:Question 8Select one:a.Entry to the CNS following reactivation of latent virus within the temporal lobeb.Entry to the CNS following reactivation of latent virus within trigeminal ganglionc.Passage across the blood-brain barrier following inflammationd.Movement of virus from cold sores directly to the CNS through peripheral nerves
Question
Encephalitis caused by HSV1 (cold sore virus) commonly involves:Question 8Select one:a.Entry to the CNS following reactivation of latent virus within the temporal lobeb.Entry to the CNS following reactivation of latent virus within trigeminal ganglionc.Passage across the blood-brain barrier following inflammationd.Movement of virus from cold sores directly to the CNS through peripheral nerves
Solution
The correct answer is:
b. Entry to the CNS following reactivation of latent virus within trigeminal ganglion
Here's why:
Herpes Simplex Virus 1 (HSV1), the virus that causes cold sores, establishes latency in the trigeminal ganglion, a group of nerve cells near the ear. When the virus reactivates, it travels along the nerves to the skin, causing cold sores. However, in rare cases, the virus can travel to the brain,
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