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Which of these statements is correct regarding the aetiology and pathogenesis of chronic bronchitis?Question 6Answera.It is characterised by loss of both radial traction and alveolar surface area.b.It is characterised by reduced numbers of goblet cells and sub-mucosal glands in the bronchi and bronchioles.c.It is typically associated with reduced bacterial and viral infections.d.The incidence tends to be lowest among heavy cigarette smokers.e.The disease is associated with metaplasia of epithelial cells in the bronchi.

Question

Which of these statements is correct regarding the aetiology and pathogenesis of chronic bronchitis?Question 6Answera.It is characterised by loss of both radial traction and alveolar surface area.b.It is characterised by reduced numbers of goblet cells and sub-mucosal glands in the bronchi and bronchioles.c.It is typically associated with reduced bacterial and viral infections.d.The incidence tends to be lowest among heavy cigarette smokers.e.The disease is associated with metaplasia of epithelial cells in the bronchi.

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Solution

The correct statement regarding the aetiology and pathogenesis of chronic bronchitis is: "The disease is associated with metaplasia of epithelial cells in the bronchi."

Here's why:

a. Chronic bronchitis is characterized by increased mucus production and not by loss of both radial traction and alveolar surface area. The latter is more associated with emphysema.

b. Chronic bronchitis is actually characterized by an increase in the number of goblet cells and submucosal glands in the bronchi and bronchioles, not a reduction. These changes lead to excessive mucus production, a hallmark of the disease.

c. Chronic bronchitis is typically associated with increased, not reduced, bacterial and viral infections. These infections can trigger exacerbations of the disease.

d. The incidence of chronic bronchitis is highest, not lowest, among heavy cigarette smokers. Smoking is a major risk factor for the development of the disease.

e. Chronic bronchitis is indeed associated with metaplasia of epithelial cells in the bronchi. This means that the normal cells of the bronchi are replaced with cells that are not typically found in that location, often as a response to chronic irritation or inflammation.

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Similar Questions

Which of these statements is/are correct relating to the aetiology and pathogenesis of emphysema?Question 42Answera.Excessive protease activity will typically increase destruction of the alveolar walls.b.A strong inflammatory response and increased neutrophil activity can lead to reduced alveolar damage.c.Cigarette smoking leads to emphysema by inducing metaplasia in the bronchioles.d.Emphysema is most commonly a consequence of pneumonia.e.Bacterial infection, excess mucus production and mucus gland hyperplasia are key factors.

Which of the following are typical consequences/complications in an individual with chronic bronchitis?W. Apoptosis of cells in sub-mucosal glands leading to reduced mucus production.X.  Cardiac tamponade.Y.  Left-sided heart failure.Z.  Respiratory acidosis and cyanosis.Question 53Select one:a.if only W, X and Y are correctb.if only W and Y are correctc.if only X and Z are correctd.if only Z is correcte.if all are correct

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A person with predominant emphysema……Question 30Select one:a.Typically has a dry (non-productive) cough.b.Usually presents with cyanosis.c.Has a loss of usable bronchial surface area.d.Typically has a decreased respiratory rate.e.None of the above are correct.

Which of these signs, symptoms and pathological hallmarks is attributed to the correct disease?Question 44Answera.Increased protease and reduced anti-protease activity in alveoli - EMPHYSEMA.b.Excess chloride ion excretion from cells and thin, watery mucus in lungs - CYSTIC FIBROSIS.c.Reduced inflammation in lungs, no alveolar wall damage and high blood O2 saturation - COVID-19.d.Increased respiratory rate and reduced CO2 in blood - CHRONIC BRONCHITIS.e.Metaplasia of epithelial cells in the bronchi - PNEUMONIA.

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