Select the correct statements. (Note that there may be more than one correct statement.)Group of answer choicesIncreased sympathetic activity results in an increased activation of α1 adrenoreceptors, which profoundly increases heart rate and therefore cardiac output.Statins decrease plasma LDL concentration because they inhibit an enzyme that is involved in hepatic cholesterol synthesis.Hypertension damages endothelium and therefore accelerates the development of atherosclerotic plaques.Systemic vasoconstriction increases total peripheral resistance and therefore increases mean arterial pressure, too.
Question
Select the correct statements. (Note that there may be more than one correct statement.)Group of answer choicesIncreased sympathetic activity results in an increased activation of α1 adrenoreceptors, which profoundly increases heart rate and therefore cardiac output.Statins decrease plasma LDL concentration because they inhibit an enzyme that is involved in hepatic cholesterol synthesis.Hypertension damages endothelium and therefore accelerates the development of atherosclerotic plaques.Systemic vasoconstriction increases total peripheral resistance and therefore increases mean arterial pressure, too.
Solution
The correct statements are:
-
"Statins decrease plasma LDL concentration because they inhibit an enzyme that is involved in hepatic cholesterol synthesis." This is correct because statins work by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol in the liver. By inhibiting this enzyme, statins reduce the amount of cholesterol produced, which leads to a decrease in LDL (low-density lipoprotein) cholesterol levels in the blood.
-
"Hypertension damages endothelium and therefore accelerates the development of atherosclerotic plaques." This is correct because high blood pressure can damage the endothelium, the inner lining of the arteries. This damage can lead to the formation of atherosclerotic plaques, which are deposits of cholesterol and other substances on the inner walls of the arteries.
-
"Systemic vasoconstriction increases total peripheral resistance and therefore increases mean arterial pressure, too." This is correct because vasoconstriction, or the narrowing of the blood vessels, increases the resistance to blood flow. This increased resistance can lead to an increase in mean arterial pressure, which is the average pressure in a person's arteries during one cardiac cycle.
The statement "Increased sympathetic activity results in an increased activation of α1 adrenoreceptors, which profoundly increases heart rate and therefore cardiac output." is not entirely correct. While increased sympathetic activity does result in the activation of α1 adrenoreceptors, this primarily leads to vasoconstriction, not an increase in heart rate. The β1 adrenoreceptors are more involved in increasing heart rate and cardiac output.
Similar Questions
Select the correct statements. (Note that there may be more than one correct statement.)Group of answer choicesStatins decrease plasma LDL concentration because they inhibit an enzyme that is involved in hepatic cholesterol synthesis.Systemic vasoconstriction increases total peripheral resistance and therefore increases mean arterial pressure, too.Increased sympathetic activity results in an increased activation of α1 adrenoreceptors, which profoundly increases heart rate and therefore cardiac output.Hypertension damages endothelium and therefore accelerates the development of atherosclerotic plaques.
Statins are widely used to reduce blood cholesterol levels by slowing down the rate of fatty material deposits. A reported side effect of taking statins is that they also reduce blood pressure. A sample of patients with high blood cholesterol was offered statins as treatment. Their blood pressure was taken before treatment started and at weekly intervals.Table 2 shows the percentage of patients with lower blood pressure several weeks after starting treatment. 440 patients took statins and 300 patients took a placebo (not statins).Explain the conclusion that statins reduce blood pressure.
Which of the following would result in a decrease in arterial blood pressure?Question 6Select one:a.Increased blood volumeb.Increased sympathetic stimulationc.Increased heart rated.Increased stroke volumee.Increased arteriolar vasodilationClear my choice
Q9. Which one of the following would result in a DECREASE in blood pressure?a) increased heart rateb) increased diameter of blood vesselsc) increase in sympathetic stimulation to the heartd) increase in blood viscosity
Statins are medicines which reduce blood cholesterol levels. Different medicines, called ACEinhibitors, can reduce blood pressure.Suggest why statins and ACE inhibitors are only given to individuals with high cholesterol orblood pressure........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ [2](c) Scientists wanted to know if taking statins and ACE inhibitors would reduce the risk ofdeveloping CVD in people with average blood pressure. The scientists recorded the bloodpressure and age of every person who took part in the study.(i) Suggest one more piece of information that would be useful to know about the peoplein the study....................................................................................................................................... [1](ii) The people taking part in the study were put in two groups. One group was given aplacebo. The other group was given statins and ACE inhibitors.Explain why it was ethical to use a placebo in this study........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ [2]
Upgrade your grade with Knowee
Get personalized homework help. Review tough concepts in more detail, or go deeper into your topic by exploring other relevant questions.