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Roger Sperry's chemoaffinity hypothesisGroup of answer choicesarises from the fact that frog axons are able to regenerate.is supported by the orderly reinnervation of the frog optic tectum by regenerating retinal ganglion cells.correctly predicted that each optic tectal neuron–retinal axon pair would have a unique molecular lock-and-key recognition signal.was based upon his discovery of cell adhesion molecules in the optic tectum.relies on the random innervation of the optic tectum by retinal neurons

Question

Roger Sperry's chemoaffinity hypothesisGroup of answer choicesarises from the fact that frog axons are able to regenerate.is supported by the orderly reinnervation of the frog optic tectum by regenerating retinal ganglion cells.correctly predicted that each optic tectal neuron–retinal axon pair would have a unique molecular lock-and-key recognition signal.was based upon his discovery of cell adhesion molecules in the optic tectum.relies on the random innervation of the optic tectum by retinal neurons

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Solution

Roger Sperry's chemoaffinity hypothesis is supported by the orderly reinnervation of the frog optic tectum by regenerating retinal ganglion cells. This hypothesis suggests that each neuron has a unique chemical identity that allows it to connect with specific target cells during development. This idea was supported by experiments showing that when the optic nerve of a frog is cut and allowed to regenerate, the retinal ganglion cells are able to reestablish their original connections in the optic tectum. This suggests that there is a specific chemical signal that guides these cells back to their original targets. This hypothesis does not rely on the random innervation of the optic tectum by retinal neurons, but rather suggests a highly specific and ordered process of reinnervation.

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