Genes in some viruses—including HIV and COVID—consist of RNA. During an infection, special machines make a DNA copy of the virus's genes. Suppose that one of these viruses had the following RNA sequence: UUAAGCGCGUC. What would the DNA copy of this sequence--meaning, the DNA produced as a complementary sequence--look like? (As usual, all sequences are written 5' to 3' here.)
Question
Genes in some viruses—including HIV and COVID—consist of RNA. During an infection, special machines make a DNA copy of the virus's genes. Suppose that one of these viruses had the following RNA sequence: UUAAGCGCGUC. What would the DNA copy of this sequence--meaning, the DNA produced as a complementary sequence--look like? (As usual, all sequences are written 5' to 3' here.)
Solution
The DNA copy of the RNA sequence UUAAGCGCGUC would be AATTGCGCGAG. This is because in DNA, Adenine (A) pairs with Thymine (T), and Guanine (G) pairs with Cytosine (C). In RNA, Uracil (U) is used instead of Thymine (T), so when transcribing from RNA to DNA, Uracil (U) becomes Adenine (A).
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