Which of the following is false? Hormone receptors may be found in the nucleus of cells. Thyroid hormones are transported as free hormones in the blood. C cells play an important roles in calcium homeostasis. There is 20-fold more T4 compared to T3 hormone in the human body.
Question
Which of the following is false? Hormone receptors may be found in the nucleus of cells. Thyroid hormones are transported as free hormones in the blood. C cells play an important roles in calcium homeostasis. There is 20-fold more T4 compared to T3 hormone in the human body.
Solution
The false statement is: "Thyroid hormones are transported as free hormones in the blood."
In reality, thyroid hormones are primarily transported in the blood bound to carrier proteins. Only a small fraction of the total thyroid hormones (T3 and T4) in the blood are free (unbound) and biologically active.
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