In which form is CO₂ transported in blood plasma?
Question
In which form is CO₂ transported in blood plasma?
Solution
CO₂ is transported in blood plasma primarily in the form of bicarbonate ions (HCO₃⁻). Here's the step-by-step process:
- Carbon dioxide (CO₂) produced by cells during metabolism diffuses into the blood.
- Once in the blood, a small portion of the CO₂ remains as is, dissolved in the plasma.
- The majority of the CO₂, however, diffuses into red blood cells.
- Inside the red blood cells, CO₂ combines with water (H₂O) in a reaction catalyzed by the enzyme carbonic anhydrase. This reaction forms carbonic acid (H₂CO₃).
- Carbonic acid is unstable in the blood and quickly dissociates into bicarbonate ions (HCO₃⁻) and hydrogen ions (H⁺).
- The bicarbonate ions diffuse out of the red blood cells and into the plasma, where they are transported to the lungs. The hydrogen ions remain inside the red blood cells.
- In the lungs, the process is reversed: bicarbonate ions are converted back into CO₂, which is exhaled.
So, while some CO₂ is transported in the plasma as dissolved gas, the majority is carried as bicarbonate ions.
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