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Chargaff’s rules states that:Answers: A. The amount of guanine equals the amount of cytosineB. The amount of adenine equals the amount of cytosineC. The amount of purines equals the amount of pyrimidinesD. The amount of adenine equals the amount of thymineE. The amount of guanine equals the amount of thymine

Question

Chargaff’s rules states that:Answers: A. The amount of guanine equals the amount of cytosineB. The amount of adenine equals the amount of cytosineC. The amount of purines equals the amount of pyrimidinesD. The amount of adenine equals the amount of thymineE. The amount of guanine equals the amount of thymine

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Solution

Chargaff's rules, named after biochemist Erwin Chargaff, state that in DNA:

A. The amount of guanine equals the amount of cytosine. This is true because guanine and cytosine pair together in the DNA double helix.

D. The amount of adenine equals the amount of thymine. This is also true because adenine and thymine pair together in the DNA double helix.

So, the correct answers are A and D.

C. The amount of purines equals the amount of pyrimidines. This is also true because adenine and guanine are purines and they pair with thymine and cytosine, which are pyrimidines. However, this is not explicitly stated in Chargaff's rules.

B. The amount of adenine equals the amount of cytosine and E. The amount of guanine equals the amount of thymine are not true according to Chargaff's rules. Adenine pairs with thymine and guanine pairs with cytosine. Therefore, the amount of adenine should equal the amount of thymine, not cytosine, and the amount of guanine should equal the amount of cytosine, not thymine.

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