The correct statement regarding apoptosis is "Apoptosis is a response to external or internal cellular and genomic stress."

Explanation:

1. Apoptosis is a process of programmed cell death that occurs in multicellular organisms. It is a response to external or internal cellular and genomic stress, not a unique property of cancer cells.

2. Both intrinsic and extrinsic apoptosis processes can involve the release of cytochrome C from mitochondria. The intrinsic pathway is triggered by internal stress signals, resulting in mitochondrial outer membrane permeabilization (MOMP) and the release of cytochrome C. The extrinsic pathway is triggered by external signals, but can also lead to MOMP and cytochrome C release in certain conditions.

3. p53 activation does not always result in apoptosis. p53 is a tumor suppressor protein that regulates the cell cycle and functions as a transcription factor to activate the expression of various genes. Depending on the type and extent of cellular stress, p53 activation can lead to cell cycle arrest, DNA repair, senescence, or apoptosis.

Question

The correct statement regarding apoptosis is "Apoptosis is a response to external or internal cellular and genomic stress."

Explanation:

1. Apoptosis is a process of programmed cell death that occurs in multicellular organisms. It is a response to external or internal cellular and genomic stress, not a unique property of cancer cells.

2. Both intrinsic and extrinsic apoptosis processes can involve the release of cytochrome C from mitochondria. The intrinsic pathway is triggered by internal stress signals, resulting in mitochondrial outer membrane permeabilization (MOMP) and the release of cytochrome C. The extrinsic pathway is triggered by external signals, but can also lead to MOMP and cytochrome C release in certain conditions.

3. p53 activation does not always result in apoptosis. p53 is a tumor suppressor protein that regulates the cell cycle and functions as a transcription factor to activate the expression of various genes. Depending on the type and extent of cellular stress, p53 activation can lead to cell cycle arrest, DNA repair, senescence, or apoptosis.

Knowee AI · Accepted Answer

The correct statement regarding apoptosis is "Apoptosis is a response to external or internal cellular and genomic stress."

Explanation:

1. Apoptosis is a process of programmed cell death that occurs in multicellular organisms. It is a response to external or internal cellular and genomic stress, not a unique property of cancer cells.

2. Both intrinsic and extrinsic apoptosis processes can involve the release of cytochrome C from mitochondria. The intrinsic pathway is triggered by internal stress signals, resulting in mitochondrial outer membrane permeabilization (MOMP) and the release of cytochrome C. The extrinsic pathway is triggered by external signals, but can also lead to MOMP and cytochrome C release in certain conditions.

3. p53 activation does not always result in apoptosis. p53 is a tumor suppressor protein that regulates the cell cycle and functions as a transcription factor to activate the expression of various genes. Depending on the type and extent of cellular stress, p53 activation can lead to cell cycle arrest, DNA repair, senescence, or apoptosis.

Question

Solution

Similar Questions

Upgrade your grade with Knowee