After a blood test, an adult patient is shown to have elevated blood levels of IGF-1, and scans reveal a pituitary mass that is diagnosed as an adenoma. There is evidence of connective tissue overgrowth such as enlarged hands, feet and jaw. a. What specific region of the pituitary is involved (1 mark)? b. What is the major mediating hormone for your current observations in this patient (1 mark)? c. What is the diagnosis of this patient (1 mark)? d. What is the juvenile form of this disease that it needs to be differentiated from (1 mark)?
Question
After a blood test, an adult patient is shown to have elevated blood levels of IGF-1, and scans reveal a pituitary mass that is diagnosed as an adenoma. There is evidence of connective tissue overgrowth such as enlarged hands, feet and jaw. a. What specific region of the pituitary is involved (1 mark)? b. What is the major mediating hormone for your current observations in this patient (1 mark)? c. What is the diagnosis of this patient (1 mark)? d. What is the juvenile form of this disease that it needs to be differentiated from (1 mark)?
Solution 1
a. The specific region of the pituitary involved is the anterior pituitary.
b. The major mediating hormone for the current observations in this patient is Growth Hormone (GH).
c. The diagnosis of this patient is Acromegaly.
d. The juvenile form of this disease that it needs to be differentiated from is Gigantism.
Solution 2
a. The specific region of the pituitary involved is the anterior pituitary.
b. The major mediating hormone for the current observations in this patient is Growth Hormone (GH).
c. The diagnosis of this patient is Acromegaly.
d. The juvenile form of this disease that it needs to be differentiated from is Gigantism.
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