What mechanism does the parasympathetic nervous system use to decrease heart rate?Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer.aDirect couplingbIP3/DAG second messengercEnzyme linkeddcAMP second messenger
Question
What mechanism does the parasympathetic nervous system use to decrease heart rate?Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer.aDirect couplingbIP3/DAG second messengercEnzyme linkeddcAMP second messenger
Solution
The parasympathetic nervous system decreases heart rate through a mechanism known as direct coupling. Here's a step-by-step explanation:
- The parasympathetic nervous system is activated, which is often in response to a calm or relaxed state.
- This activation triggers the release of the neurotransmitter acetylcholine.
- Acetylcholine binds to muscarinic receptors (specifically M2 receptors) on the pacemaker cells of the heart.
- This binding causes a G protein inside the cell to activate, which is the "direct coupling" part of the process.
- The activated G protein then opens potassium channels in the cell membrane.
- The opening of these channels allows potassium ions to leave the cell, which hyperpolarizes the cell and makes it less likely to fire.
- This decrease in cell firing leads to a slower heart rate.
So, the answer is a) Direct coupling.
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