The mutation c.546delT is :nucleotide T is deleted from cDNA position 546duplication of T at 546codon 546 has become TTTamino acid T is deleted from position 546
Question
The mutation c.546delT is :nucleotide T is deleted from cDNA position 546duplication of T at 546codon 546 has become TTTamino acid T is deleted from position 546
Solution
The mutation c.546delT refers to the deletion of the nucleotide Thymine (T) at the 546th position in the cDNA sequence. This does not mean that the codon 546 has become TTT or that the amino acid T is deleted from position 546. It simply means that one instance of the nucleotide T has been removed from the 546th position in the cDNA sequence. This can potentially lead to a frameshift mutation, which could alter the amino acid sequence during protein synthesis.
Similar Questions
The original strand of DNA looks like this ACGTCTCGA. The mutated strand looks like this ACGTTCGA. What type of mutation is this?*1 pointTranslocationNucleotide base deletionNucleotide base insertionNucleotide base substitution
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