Terminology associated with serum drug levelsSerum drug levelsTherapeutic indexMinimal effective concentrationTherapeutic levelToxic levelSerum half-life

One of the following is not correct about the trough level of a drug:Question 38Answera.Trough level is used as a marker of drug exposure.b.Trough level is the concentration of the drug in the blood immediately before the next dose is administered.c.The highest level of medication in the bloodd.Trough level indicates the lowest concentration in an individual's body.

What term is used to describe a decrease in responsiveness to a drug that develops in a few minutes?a.Refractorinessb.Cumulative effectc.Toleranced.Tachyphylaxis

Does IVIVC match this definition, This indicates the correlation between lab test results and drug product performance in a live patient.

What term is used to describe a decrease in responsiveness to a drug that develops in a few minutes?a.Tachyphylaxisb.Refractorinessc.Toleranced.Cumulative effect

Match each term to the correct definition or description. - topical dermatological - transdermal product - ointments, creams, and gels - stratum corneum - suppository - solubility - elixir - disperse system A. solid dosage form in which active ingredients are dispersed in a suitable base and molded or shaped for insertion into a natural body opening to provide a local or systemic effect B. semisolid dosage forms intended for application topically: on the skin; in the eye or nostrils or other openings of the body, for local effect or systemic absorption C. the degree to which the cohesive forces holding a solute together are overcome by forces of attraction between the solute and the solvent molecules so the solute will be evenly dispersed in the solvent D. a clear, sweetened hydroalcoholic solution administered orally, used as a vehicle for a drug or for the therapeutic effect of the API they contain E. mixture containing an undissolved or immiscible drug distributed throughout a vehicle; can be solid in liquid, liquid in liquid and gas in liquid F. product is designed to deliver API through the skin by percutaneous absorption to the general circulation, the skin is not the target organ G. keratinized layer of skin that is the main barrier to percutaneous absorption of transdermal drugs; it behaves like a semipermeable membrane, drug molecules penetrate it by passive diffusion H. product is administered onto and/or into the skin, the skin itself is the target organ