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Which of the following proteins would you expect to be made by a ribosome that does not attach to the ER? A hormone that travels in the bloodstream. An enzyme that is used in glycolysis. Collagen. Amylase (used to digest starch).

Question

Which of the following proteins would you expect to be made by a ribosome that does not attach to the ER? A hormone that travels in the bloodstream. An enzyme that is used in glycolysis. Collagen. Amylase (used to digest starch).

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Solution

An enzyme that is used in glycolysis.

This is because glycolysis occurs in the cytoplasm of the cell, and the enzymes that facilitate this process are also produced there. Ribosomes that are not attached to the endoplasmic reticulum (ER) are called free ribosomes, and they float in the cytoplasm. Therefore, they are responsible for synthesizing proteins that function in the cytoplasm, like the enzymes used in glycolysis.

On the other hand, proteins like hormones that travel in the bloodstream, collagen, and amylase are typically synthesized by ribosomes attached to the ER because they are either secreted from the cell or incorporated into the cell membrane.

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