Researchers interested in studying a certain cyto- chrome P450 enzyme wish to isolate the enzyme of interest from the many other proteins in the cells. One of their initial steps is to lyse the cells and isolate the organelle which carries the enzyme they want to study. Which organelle will they isolate to find CYP enzymes? * (A) Golgi apparatus (B) Lysosomes (C) Mitochondria (D) Peroxisomes (E) Smooth endoplasmic reticulum
Question
Researchers interested in studying a certain cyto- chrome P450 enzyme wish to isolate the enzyme of interest from the many other proteins in the cells. One of their initial steps is to lyse the cells and isolate the organelle which carries the enzyme they want to study. Which organelle will they isolate to find CYP enzymes? * (A) Golgi apparatus (B) Lysosomes (C) Mitochondria (D) Peroxisomes (E) Smooth endoplasmic reticulum
Solution
The cytochrome P450 enzymes are primarily found in the Smooth Endoplasmic Reticulum (SER) of the cells. So, the researchers will isolate the Smooth Endoplasmic Reticulum to study the CYP enzymes. Therefore, the answer is (E) Smooth endoplasmic reticulum.
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