The antigen binding cleft on the class I MHC is formed by the interaction of the _______, and the antigen biding cleft has a (n) ______ binding cleft.1 point a1 and a2 domains; open a1 and a2 domains; closed a2 and a3 domains; open a2 and a3 domains; closed

Class I MHC molecule can ____________.bind to CD8 molecules on T cellspresent antigens to B cellsbind to CD4 molecules on T cellsbind to antibodies

Compared to the MHC molecule on the left, the MHC molecule on the right (in the drawing above) will bind a ______ peptide that, if foreign, will cause a T cell to activate and _________. The protein on the left is made up of two peptides, each with two domains. One peptide has domains labeled alpha 1 and 2, the other beta 1 and 2. The protein on the right is made up of two peptides, one with three domains labeled alpha 1, 2 and 3 and the other a single domain labeled beta MG.

CD4 attaches to the base of MHC _______ and stabilizes the binding of antigen to the αβ receptors of ________ cells.1 pointI; TCI; THII; TCII; TH

The β microglobulin molecule has the most significant sequence homology to the _____ domain of MHC II. However, unlike this domain, it does not have a (n) _______.1 pointβ1; antigen binding siteβ1; membrane-spanning domainβ2; antigen binding siteβ2; membrane-spanning domain

Regarding the major histocompatibility class II (MHC II) molecule, which of the following statements is TRUE?Select one alternative:Antigenic peptides are anchored along the peptide binding groove in MHC II.Each MHC II molecule can present only one specific (cognate) antigen.MHC II molecules present endogenous antigens, from within the cell.MHC II is expressed on all nucleated cells in the body.