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State the virulence factor used by Clostridium perfringens to cause an infection.

Question

State the virulence factor used by Clostridium perfringens to cause an infection.

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Solution

Clostridium perfringens, a bacterium that can cause food poisoning and other illnesses, uses several virulence factors to cause an infection. Here are the steps to answer your question:

  1. Understand the term "virulence factor": A virulence factor is a molecule or a cell structure that supports a microbe to establish itself on or within a host of a particular species and enhances the potential to cause disease.

  2. Identify the virulence factors of Clostridium perfringens: Clostridium perfringens produces several toxins that are virulence factors. The most significant one is the alpha toxin (also known as perfringolysin O), which has phospholipase C activity that can degrade tissue and cell membranes, leading to cell death.

  3. State the virulence factor: Therefore, the virulence factor used by Clostridium perfringens to cause an infection is primarily the alpha toxin. Other toxins such as enterotoxin and beta2 toxin also contribute to the pathogenicity of this bacterium.

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