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Which of the following proteins requires post-translational control in order to function?That is, which of the following proteins is unable to perform its function immediately followingtranslation?1. CDK 22. channelrhodopsin3. CED 3 caspase4. bicoid proteinA. 1, 2 and 3B. 1 and 3C. 2 and 4D. 4 onlyE. All of 1, 2, 3 and 4 are correct

Question

Which of the following proteins requires post-translational control in order to function?That is, which of the following proteins is unable to perform its function immediately followingtranslation?1. CDK 22. channelrhodopsin3. CED 3 caspase4. bicoid proteinA. 1, 2 and 3B. 1 and 3C. 2 and 4D. 4 onlyE. All of 1, 2, 3 and 4 are correct

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Solution

The answer to this question depends on the specific post-translational modifications and control mechanisms required for each protein to function.

  1. CDK 2 (Cyclin-dependent kinase 2) is a protein that requires post-translational modifications to be activated. It is involved in the regulation of the cell cycle and its activity is controlled by cyclins and cyclin-dependent kinase inhibitors.

  2. Channelrhodopsin is a light-gated ion channel found in the plasma membrane of Chlamydomonas reinhardtii. It does not require post-translational modifications to function.

  3. CED 3 caspase is a cysteine-aspartic protease that plays a central role in the execution-phase of cell apoptosis. It is synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis.

  4. Bicoid protein is a maternal effect protein responsible for anterior-posterior axis formation in Drosophila. It is translated from mRNA that has been localized to the anterior end of the egg during oogenesis.

So, the proteins that require post-translational control in order to function are CDK 2 and CED 3 caspase. Therefore, the correct answer is B. 1 and 3.

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