Question 2The use of prisoners in research is a concern under the Belmont principle of Justice because: Prisoners are not a representative sample of the general population Prisoners may not be used to conduct research that only benefits the larger society Prisoners are less educated that the general population and have difficulty understanding research Prisoners are not free to say noQuestion 3Informed consent is considered an application of which Belmont principle? Beneficence Justice Non-maleficence Respect for PersonsQuestion 4Which of the following is included in the Nuremberg Code: Confidentiality of data Voluntary consent Equitable selection of subjects Additional protection for vulnerable subjectsQuestion 5The National Research Act of 1974 Identified guidelines to ensure the ethical conduct of research. Identified the basic ethical principles of human subjects research. Required that all federal agencies have the same regulations governing human subjects research. Established the National Commission.

Question 1Which of the following brought increased public attention to the problems with the IRB system? Death of Research Subject (Jesse Gelsinger) HHS Inspector General Report of 1998 “Shut Downs” by OHRP 1983 Presidential Commission ReportQuestion 2The use of prisoners in research is a concern under the Belmont principle of Justice because: Prisoners are not a representative sample of the general population Prisoners may not be used to conduct research that only benefits the larger society Prisoners are less educated that the general population and have difficulty understanding research Prisoners are not free to say noQuestion 3Informed consent is considered an application of which Belmont principle? Beneficence Justice Non-maleficence Respect for PersonsQuestion 4Which of the following is included in the Nuremberg Code: Confidentiality of data Voluntary consent Equitable selection of subjects Additional protection for vulnerable subjectsQuestion 5The National Research Act of 1974 Identified guidelines to ensure the ethical conduct of research. Identified the basic ethical principles of human subjects research. Required that all federal agencies have the same regulations governing human subjects research. Established the National Commission.

According to the Belmont Report, the requirement that the benefits and burdens of the research are equitably distributed, expresses the principle of: Justice Beneficence Respect for persons

Question 1Which of the following is an example of how the principle of beneficence can be applied to a study employing human subjects? Ensuring that persons with diminished autonomy are protected. Providing detailed information about the study and obtaining the subject's consent to participate. Determining that the study has a maximization of benefits and a minimization of risks. Ensuring that the selection of subjects includes people from all segments of the population.Question 2The Belmont Report’s principle of respect for persons incorporates at least two ethical convictions: first, that individuals should be treated as autonomous agents, and second, that: Persons with diminished autonomy should be excluded from research. Persons with diminished autonomy should only participate in no more than minimal risk research. Persons with diminished autonomy are entitled to protection. Persons involved in research cannot financially benefit.Question 3Which of the following are the three principles discussed in the Belmont Report? Informed Consent, Institutional Assurance, Researcher Responsibility Respect for Persons, Beneficence, Justice IRB Review, Federal Regulations, Declaration of Helsinki Privacy, Confidentiality, Equitable Selection of Subjects

An example cited in the Belmont Report (The National Commission 1979) stated that "During the 19th and early 20th centuries the burdens of serving as research subjects fell largely upon poor ward patients, while the benefits of improved medical care flowed primarily to private patients." This is an example of a violation of which Belmont principle? Respect for persons Beneficence Justice

The Belmont Report’s principle of respect for persons incorporates at least two ethical convictions: first, that individuals should be treated as autonomous agents, and second, that: Persons with diminished autonomy are entitled to protection. Persons with diminished autonomy should be excluded from research. Persons with diminished autonomy should only participate in no more than minimal risk research. Persons involved in research cannot financially benefit.