Which of the following are correct statements about hemolytic transfusion reactions?SELECT ALL THAT APPLYSigns and symptoms tend to occur within hours of incompatible transfusion.Signs and symptoms may include wheezing, cough, and shortness of breath.Unfortunately, transfusion reactions are hard to avoid due to difficulty in identifying red blood cell antigens from individual donors and recipients.Multiple therapies are available to reverse a transfusion reaction or block one once it starts.A hemolytic transfusion reaction, which lyses red blood cells, could kill the patient.The most crucial antigens during blood transfusion are those that interact with the IgE that is previously attached to mast cells in the vascular tissues
Question
Which of the following are correct statements about hemolytic transfusion reactions?SELECT ALL THAT APPLYSigns and symptoms tend to occur within hours of incompatible transfusion.Signs and symptoms may include wheezing, cough, and shortness of breath.Unfortunately, transfusion reactions are hard to avoid due to difficulty in identifying red blood cell antigens from individual donors and recipients.Multiple therapies are available to reverse a transfusion reaction or block one once it starts.A hemolytic transfusion reaction, which lyses red blood cells, could kill the patient.The most crucial antigens during blood transfusion are those that interact with the IgE that is previously attached to mast cells in the vascular tissues
Solution
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Correct: Signs and symptoms of a hemolytic transfusion reaction often occur within hours of an incompatible transfusion.
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Correct: Signs and symptoms may include wheezing, cough, and shortness of breath. These symptoms are due to the body's immune response to the incompatible blood cells.
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Incorrect: While identifying red blood cell antigens can be complex, modern blood typing and crossmatching techniques have made transfusion reactions relatively rare.
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Correct: There are multiple therapies available to manage a transfusion reaction once it starts, including stopping the transfusion, administering fluids and medications to manage symptoms, and in severe cases, dialysis.
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Correct: A hemolytic transfusion reaction, which lyses red blood cells, can be life-threatening. This is why it's crucial to ensure blood compatibility before a transfusion.
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Incorrect: The most crucial antigens during blood transfusion are the ABO and RhD antigens. The interaction of IgE with mast cells is more related to allergic reactions, not hemolytic transfusion reactions.
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