One of the parents of a child has phenylketonuria (PKU), which is caused by recessive alleles. The other parent does not have the PKU alleles. What is the chance that the couple will have a child with phenylketonuria? Group of answer choices75%100%0%50%
Question
One of the parents of a child has phenylketonuria (PKU), which is caused by recessive alleles. The other parent does not have the PKU alleles. What is the chance that the couple will have a child with phenylketonuria? Group of answer choices75%100%0%50%
Solution
Phenylketonuria (PKU) is a genetic disorder that is inherited in an autosomal recessive manner. This means that a person must inherit two copies of the defective gene (one from each parent) in order to develop the disease.
In this case, one parent has PKU, meaning they have two copies of the defective gene (let's denote them as "aa"). The other parent does not have PKU and does not carry the PKU allele, meaning they have two normal genes (let's denote them as "AA").
When these parents have a child, the child will inherit one gene from each parent. The possible combinations are:
- A from the normal parent and a from the PKU parent (Aa)
- A from the normal parent and a from the PKU parent (Aa)
In both cases, the child will be a carrier of the PKU gene but will not have the disease because they have one normal gene that can do the job.
Therefore, the chance that the couple will have a child with phenylketonuria is 0%.
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